Running increases cell proliferation and
neurogenesis in the adult mouse dentate gyrus

by
van Praag H, Kempermann G, Gage FH.
Laboratory of Genetics,
Salk Institute for Biological Studies,
La Jolla, California 92037, USA.
Nat Neurosci 1999 Mar; 2(3):266-70


ABSTRACT

Exposure to an enriched environment increases neurogenesis in the dentate gyrus of adult rodents. Environmental enrichment, however, typically consists of many components, such as expanded learning opportunities, increased social interaction, more physical activity and larger housing. We attempted to separate components by assigning adult mice to various conditions: water-maze learning (learner), swim-time-yoked control (swimmer), voluntary wheel running (runner), and enriched (enriched) and standard housing (control) groups. Neither maze training nor yoked swimming had any effect on bromodeoxyuridine (BrdU)-positive cell number. However, running doubled the number of surviving newborn cells, in amounts similar to enrichment conditions. Our findings demonstrate that voluntary exercise is sufficient for enhanced neurogenesis in the adult mouse dentate gyrus.

BDNF
Jogging
Exercise
Hypericum
Nicergoline
Vasopressin
New brain cells
The memory switch?
Growing new brain cells
Smart drugs and aging brains
Scepticism about smart drugs



Refs
and further reading

HOME
HedWeb
Nootropics
erythroxylum-coca.com
Future Opioids
BLTC Research
MDMA/Ecstasy
Superhapiness?
Utopian Surgery?
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World

The Good Drug Guide
The Good Drug Guide

The Responsible Parent's Guide
To Healthy Mood Boosters For All The Family