Piracetam: a review of pharmacological
properties and clinical uses
Karolinska Institutet, Neurotec,
Huddinge, University Hospital B 84,
S-14186 Stockholm, Sweden.
CNS Drug Rev. 2005 Summer;11(2):169-82.
ABSTRACTPiracetam, a derivative of the neurotransmitter gamma-aminobutyric acid (GABA), has a variety of physiological effects that may result, at least in part, from the restoration of cell membrane fluidity. At a neuronal level, piracetam modulates neurotransmission in a range of transmitter systems (including cholinergic and glutamatergic), has neuroprotective and anticonvulsant properties, and improves neuroplasticity. At a vascular level, it appears to reduce erythrocyte adhesion to vascular endothelium, hinder vasospasm, and facilitate microcirculation. This diverse range of physiological effects is consistent with its use in a range of clinical indications. Its efficacy is documented in cognitive disorders and dementia, vertigo, cortical myoclonus, dyslexia, and sickle cell anemia. While high doses are sometimes necessary, piracetam is well tolerated.Piracetam
New brain cells
The memory switch?
Growing new brain cells
Piracetam and dopamine
Piracetam and working memory
Piracetam and the mitochondria
Refsand further reading
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
Critique of Huxley's Brave New World
The Good Drug Guide
The Responsible Parent's Guide
To Healthy Mood Boosters For All The Family