Cognitive function in healthy older European adults: the ZENITH study
Simpson EE, Maylor EA, Rae G, Meunier N,
Andriollo-Sanchez M, Catasta G, McConville C, Ferry M,
Polito A, Stewart-Knox BJ, Secker DL, Coudray C.
School of Psychology/NICHE University of Ulster,
Northern Ireland, UK.
Eur J Clin Nutr. 2005 Nov;59 Suppl 2:S26-30.
ABSTRACTOBJECTIVE: as assessed by the CANTAB computerised test battery. DESIGN: This is a multicentre prospective intervention study employing a randomised double-blind design. SETTING: European community-based study. PARTICIPANTS: There are 387 healthy adults aged 55-87 y from centres in France, Italy and Northern Ireland. INTERVENTIONS: Measures of visual memory, working memory and attention were obtained at baseline (prior to supplementation). RESULTS: Younger adults (<70 y) performed significantly better than older adults (>70 y) on all tests, with minimal differences between centres. In addition, men outperformed women on tests of spatial span, pattern recognition memory and reaction times, although these gender differences varied somewhat between centres. CONCLUSIONS: The results are generally consistent with previous age- and gender-related effects on cognitive functioning.Zinc
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